OralEscherichia coliColonization Factor Antigen I Fimbriae Ameliorate Arthritis via IL-35, Not IL-27
نویسندگان
چکیده
منابع مشابه
Oral Escherichia coli colonization factor antigen I fimbriae ameliorate arthritis via IL-35, not IL-27.
A Salmonella therapeutic expressing enterotoxigenic Escherichia coli colonization factor Ag I (CFA/I) fimbriae protects against collagen-induced arthritis (CIA) by eliciting two regulatory T cell (Treg) subsets: TGF-β-producing Foxp3(-)CD39(+)CD4(+) T cells and IL-10-producing Foxp3(+)CD39(+)CD4(+) T cells. However, it is unclear whether CFA/I fimbriae alone are protective and whether other reg...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2013
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.1302018